In iontophoresis, vasodilating drugs would be used in

• A. Rheumatic diseases
• B. Peripheral vascular affections
• C. Both A and B
• D. Neither A nor B

Answer: (C)

The key idea is that delivering vasodilating drugs by iontophoresis creates a local boost in blood flow where the medicine is applied, which can help tissues that are suffering from poor perfusion or spasm. In rheumatic diseases, joints and surrounding tissues often have compromised microcirculation and inflammation; increasing local blood flow can aid healing, reduce stiffness, and alleviate pain when used alongside other therapies. In peripheral vascular affections, the goal is to improve limb perfusion by relaxing vascular smooth muscle and reducing vasospasm, which can relieve symptoms like claudication and promote tissue healing. Because iontophoresis targets the affected area with minimal systemic exposure, it’s useful in both scenarios, making the approach applicable to rheumatic conditions and to peripheral vascular problems. That shared utility is why both contexts are appropriate.