In iontophoresis, approximate current strength per square inch of electrode surface?

• A. 0.5-1
• B. 1-2
• C. 2-4
• D. 2-3

Answer: (A)

In iontophoresis, how much current per area you apply matters because the movement of ions into tissue depends on the current density at the electrode. The effective and safe range is roughly a half to one milliamp per square inch of electrode surface. This moderate density provides enough electrical force to push ions through the skin without causing irritation or damage from electrochemical reactions at the skin or electrode. If you use a higher density, you risk discomfort, redness, or burns; if you use a lower density, ion delivery becomes too slow or ineffective. So, the best guideline is about half to one milliamp per square inch to balance efficacy with safety.